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Dr Nicki Niemann, Baylor College of Medicine, USA

A long list of symptoms present in Parkinson's disease may be targeted with botulinum toxins to alleviate the burden of disease. Studies investigated its efficacy in tremor, sialorrhea, dystonia, freezing of gait, camptocormia (bent spine syndrome), urinary dysfunction, constipation, eyelid opening apraxia, blepharospasm, and in dysphagia, a condition highly prevalent in Parkinson's disease (up to 81%) which can cause serious complications.

It might be time to reconsider botulinum toxins for tremor, as botulinum toxin injections adapted to the patients are effective in controlling tremor and at the same time avoid wrist extensor inhibition and the occurrence of weakness in the hand.

Hand tremor is a common movement disorder that may be caused by essential tremor, Parkinson's disease, or dystonia. Hand tremor may be very disabling and is often associated with an impairment of quality of life despite optimal therapy. Dr Nicki Niemann (Baylor College of Medicine, USA) ...

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