Antibiotics still play an important role in hidradenitis suppurativa (HS). Overuse or arbitrary use should be avoided, stated Dr Dunja Ana Vekic (University of New South Wales, Australia).
Although HS is not primarily an infectious disease, bacteria contribute to the inflammatory drive . The microbiome of healthy skin and HS is different and bacterial biofilms possibly play a role in chronic HS [1-3]. Various guidelines suggest antibiotics in mild-to-moderate HS and also for acute lesions of all stages [1,4, 5]. Currently, clindamycin 1% is the only recommended topical therapy for mild disease as it demonstrated benefit over placebo [1,4,6]. Oral antibiotics should be given for Hurley stages 2 and 3 and non-responders to topical antibiotics . Approved agents for monotherapy are tetracycline, minocycline, and the most commonly prescribed doxycycline [1,5]. Combination therapy is recommended with clindamycin plus rifampicin .
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Table of Contents: WCD 2019
Treating Psoriasis in 2019
Atopic Dermatitis – What is New
Dermal Reactions to Systemic Drugs
Lupus Erythematosus Today
Small Molecules – What to Expect
Optimising the Management of Keloids
Malignant Melanoma – Advances in Management
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