A considerable number of patients with psoriatic arthritis (PsA) starting their first biologic treatment report unacceptable pain during the first year of treatment, even when their inflammation is controlled . Among good responders, non-inflammatory pain made up more than 80% of pain load at 3 months, indicating insufficient effects of biologics in patients with inflammation-independent pain. These findings strongly indicate a need for alternative treatment strategies in affected patients.
This study was conducted by Dr Tor Olofsson (Lund University, Sweden) et al. “It is time to shift gears. We will focus on observational studies and old medications instead of randomised controlled trials and new drugs, and we are looking at pain specifically,” said Dr Olofsson. “A swift background; when asked to prioritise between different domains in which patients are most keen on seeing an improvement, in many studies, pain has turned out as the number one. Furthe...
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