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Endoscopic treatment of asthma

Endoscopic treatment of asthma

The prevalence of asthma is increasing worldwide. However, asthma control is suboptimal in many patients. Worldwide, 250,000 lives are lost annually due to asthma. 80% of costs are driven by 20% of asthma population [14]. The pathogenesis of asthma is characterised by “an inflammatory soup”, explained Prof. Pallav Shah (Imperial College London, UK). “We start treatment with inhaled corticosteroids (ICS), but some patients become steroid dependent. We need to find those patients, because they have a high disease burden and account for the majority of costs for asthma care.”

Bronchial thermoplasty

Prof. Shah described some endoscopic treatments for severe and/or refractory asthma patients. During bronchial thermoplasty, airway smooth muscle and bronchial epithelial cells are exposed to media (37-70°C) for 10 seconds, to mimic thermoplasty [15]. These interventions have been studied in a spectrum o...



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