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Clinical utility of amyloid PET in cognitively impaired patients

A nationwide study in the USA has found that amyloid PET significantly influences clinical management, including the use of medications and counselling, of patients with mild cognitive impairment (MCI) or dementia. Changes in management were observed in about 60% of cases, more than double what the researchers had expected.

The main findings on the Imaging Dementia – Evidence for Amyloid Scanning (IDEAS) study, were presented in a plenary session by Prof. Gil Rabinovici (University of California San Francisco, USA). “IDEAS was really a nationwide effort to get evidence for the clinical utility of amyloid PET in MCI”, he stated. This was requested by the national US health insurance program Medicare. Prof Rabinovici reported results regarding the study’s first aim, which was to investigate the impact of the scan on patient management.

At 595 clinical dementia sites, 11,409 Medicare beneficiaries with MCI (60.5%) or dementia (39.5%) were recruited. “T...



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