Home > No increased cancer risk for PsA patients on TNF blockers

No increased cancer risk for PsA patients on TNF blockers

A population-based cohort study from 4 Nordic countries presented at EULAR 2019 reported that TNF inhibitors (TNFi) do not increase the incidence of cancer in psoriatic arthritis (PsA) patients compared to rates for the general population [1].

PsA is a chronic inflammatory disease that affects the joints, causing pain and disability. TNFi inhibitors have been shown to be efficacious in PsA. However, TNF also plays a role in the development and progression of cancer and therefore, use of TNFi may increase the risk of tumour development.

The current study included over 8,000 TNFi-treated PsA patients from ARTIS (Sweden), DANBIO (Denmark), ICEBIO (Iceland), and ROB-FIN (Finland), contributing a total of 44,041 patient-years of follow-up across all 4 countries. Dr Lene Dreyer et al. (Aalborg University Hospital, Denmark) followed patients from first registration with TNFi-treatment in each country and linked the data to the National Cancer Registry. Pat...



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