Home > LUTS 2-year outcomes: aquablation versus TURP

LUTS 2-year outcomes: aquablation versus TURP

According to phase 3 trial results, aquablation demonstrated a significantly lower rate of sexual dysfunction compared with transurethral resection of the prostate (TURP) at the primary safety endpoint of 3 months.

The 2-year outcomes of the WATER study were presented by Dr Neil Barber (Frimley Health NHS Foundation Trust, UK) [1]. This study compared the safety and efficacy of prostate ablation using aquablation therapy (i.e. robotic heat-free waterjet prostate resection) versus TURP for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).

In this randomised, double blinded, global multicentre phase 3 trial, 184 men with moderate-to-severe LUTS related to BPH were assigned to aquablation therapy (n=117) or TURP (n=67). Baseline characteristics of patients in both arms were comparable, with no significant differences. The trial had a co-primary safety and efficac...



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