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Endoscopic treatment of emphysema

Endoscopic treatment of emphysema

The aim of (partial) lung volume reduction in emphysema patients is “to make the lung smaller”, stated Prof. Felix Herth (UniversitätsKlinikum Heidelberg, Germany) at the beginning of his lecture. Because of the presence of hyperinflated areas in these patients, volume reduction improves breathing mechanics, exercise capacity, and quality of life, and hopefully decreases mortality. For lung volume reduction, five different techniques are available: endoscopic volume reduction surgery (EVRS), valves, coils, steam, and glue.

Evidence for lung volume reduction

Since 2002, multiple studies about lung volume reduction have been published. The most recent one was the LIBERATE study, evaluating the effectiveness of the Zephyr® Endobronchial Valve (EBV®) vs standard of care. This device provided clinically meaningful benefits in lung function, i.e. change in FEV1 ≥15% of 47.7% of patients ...



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