Two landmark trials comparing transcatheter aortic valve replacement (TAVR) with surgical aortic valve replacement (SAVR) in low-risk patients have shown promising results. The PARTNER 3 trial demonstrated that TAVR was superior to SAVR with regard to the reduction of death, stroke, or rehospitalisation at 1 year . Results from the Evolut Low Risk trial showed that TAVR with the self-expanding CoreValve was non-inferior to SAVR .
The randomised, parallel PARTNER 3 trial aimed to evaluate TAVR compared with SAVR in low-risk patients with symptomatic severe aortic stenosis. A total of 1,000 patients were enrolled in the study with a median follow-up of 1 year. Mean patient age was 73 years, 30% of patients was female, and 31% had diabetes mellitus. The mean Society of Thoracic Surgeons (STS) risk score was 1.9% (score <4% denoted ‘low-risk’, with higher scores indicating a greater risk of death within 30 days after surgery). The inclusion and exclus...
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Table of Contents: ACC 2019
Acute and Stable Ischaemic Heart Disease
Arrhythmias and Clinical Electrophysiology
Congenital Heart Disease
Heart Failure and Cardiomyopathies
Pulmonary Arterial Hypertension and Venous Thromboembolism
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