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Immediate angiography not better than delayed angiography in non-STEMI cardiac arrest patients

Conference
ACC 2019
Trial
COACT

Recent data from the COACT trial shows there may be no survival advantage when immediate coronary angiography is performed compared with delayed angiography in patients who have been successfully resuscitated after out-of-hospital cardiac arrest and who had no signs of ST-segment elevation myocardial infarction (STEMI) [1].

The Dutch multicentre COACT trial randomised 552 patients with cardiac arrest without signs of STEMI who were to undergo immediate coronary angiography (n=273) or delayed coronary angiography until after neurologic recovery (n=265). All participants underwent percutaneous coronary intervention if indicated. The primary endpoint of the trial was survival at 90 days; secondary endpoints included survival at 90 days with good cerebral performance or mild or moderate disability, myocardial injury, duration of catecholamine support, markers of shock, recurrence of ventricular tachycardia, duration of mechanical ventilation, major bleeding, o...



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