A recent trial explored a new diagnostic approach to discriminate between atopic dermatitis (AD) and psoriasis without leaving scars. The discovery of specific molecular profiles of the 2 diseases by RNA analyses of the tape-stripping samples may be of substantial future value .
When evaluating unclear inflammatory skin lesions, biopsies with histopathological investigation are still the gold standard. However, these invasive procedures can cause pain and lead to scarring, which can be especially problematic in children. Furthermore, research with therapeutic agents in children would be easier if biopsies would not be necessary. Dr Robert Bissonnette (Innovaderm Research, Canada) and his fellow researchers intended to create a sensitive yet non-invasive diagnostic tool by using tape stripping to study the genomic profile of AD and psoriasis for a skin biomarker approach to diagnosis.
Enrolled in the trial were 60 participants: 20 patients with ps...
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Table of Contents: AAD 2020
Psoriasis – What Is Hot?
Systemic Therapies for Dermatologists
Hidradenitis Suppurativa/Acne Inversa
Pearls of the Posters
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