Children with acute myeloid leukaemia (AML) from low-income neighbourhoods enrolled in phase 3 clinical trials were 2.4 times more likely to die during treatment than children from middle- and high-income neighbourhoods .
Dr Lena E. Winestone (UCSF Benioff Children’s Hospital, USA) presented the first study to demonstrate that socioeconomic status, including income and educational status, is a key contributor to survival disparities in children with AML. Researchers concluded the origin of this disparity was not from chemotherapy, but that paediatric AML patients from low-income and low-education zip codes have lower 5-year overall survival compared with patients from middle-income and higher-educated zip codes.
Data for this evaluation was obtained from 1,467 children enrolled in the Children’s Oncology Group’s 2 recent phase 3 clinical trials AAML0531 and AAML1031. Patients were assessed by the income level of their postal code and by the avera...
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Table of Contents: ASH 2019
Sickle Cell Disease
Plenary Scientific Session
CAR T and Beyond
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