Just as it was 2 years ago, almost all panellists (98.5%) endorsed neoadjuvant systemic treatment for patients with stage 2 or stage 3 triple-negative breast cancer, or with Her2-positive breast cancer. In addition, the panel this year voted about which type of neoadjuvant should be preferred in some specified subtypes of breast cancer. For example, in case of a postmenopausal patient with a luminal A subtype based on immunohistochemistry (or equivalent based on gene expression testing), 81% of the panellists preferred endocrine neoadjuvant therapy over neoadjuvant chemotherapy. This opinion means a clear shift in advantage of neoadjuvant endocrine therapy. Asked for their opinion on the appropriate duration of the endocrine neoadjuvant therapy in postmenopausal patients with a luminal A type tumour, 47% of the panellists preferred to continue endocrine neoadjuvant therapy until optimal reduction in tumour size is reached however long it takes, while 33% of the panellists preferr...
please login to read the entire article:
You need to register to read the entire article, please do so now.
« Updated Interim Results of Phase 2 Trial of Pembrolizumab for High-risk NMIBC Unresponsive to BCG Next Article
St. Gallen Consensus – Gene expression signatures »
Table of Contents: BCC 2019
St. Gallen Consensus
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. It is mandatory to procure user consent prior to running these cookies on your website.