Lung cancer is one of the primary tumours that very often spreads to the brain. If a patient presents with brain metastases of unknown origin, it is very likely that those are lung cancer metastases. Surgical removal of these lesions is not necessarily a good option, even when possible.
Approximately 13-44% of lung cancer patients develop central nervous system (CNS) metastasis; 50-60% of CNS metastases are from lung cancer. The incidence of CNS metastasis is rising, because patients are currently living longer and there is a better detection of metastasis using MRI [1,2].
Is there still a role for surgery?
Factors favouring intensified local therapy are the presence of a single or solitary metastasis, adequate performance status, no or mild neurological deficits, no or stable (>3 months) extracranial tumour manifestations, and the presence of a radioresistant tumour. “Apart from logical reasoning there is hardly any evide...
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