Home > Pulmonology > ATS 2019 > Infection > E-cigarette Use Disrupts Normal Immune Response to Viral Infections, Particularly in Women

E-cigarette Use Disrupts Normal Immune Response to Viral Infections, Particularly in Women

Presented By
Dr Meghan Rebuli, University of North Carolina at Chapel Hill, USA
Conference
ATS 2019

This preliminary study investigated differences in immune response between non-smokers and people who use cigarettes or e-cigarettes by inoculating 47 participants with live attenuated influenza virus (LAIV) [1]. They found that at baseline, e-cigarette use disrupted normal immune response to viral infections, especially for women and girls.

Smoking e-cigarettes affects the body’s response to viral infection, but the effect of using e-cigarettes is different for females and males, and it is different from the effect of smoking regular cigarettes, according to new research. The presenter, Dr Meghan Rebuli (University of North Carolina at Chapel Hill, USA) explained the immune response in female e-cigarette users was “suggestive of immunosuppression” while in males it was “a mixture of immune gene upregulation and downregulation. Any dysregulation of immune responses to pathogens has the potential to increase susceptibility to infection or vaccines,” added D...



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