Home > Pulmonology > ATS 2019 > Sleep Medicine > Sleep Apnoea Severity Has a Non-linear Relationship with Acute Myocardial Infarction Risk

Sleep Apnoea Severity Has a Non-linear Relationship with Acute Myocardial Infarction Risk

Presented By
Dr Neomi Shah, Icahn School of Medicine at Mount Sinai, USA
Conference
ATS 2019

Dr Neomi Shah (Icahn School of Medicine at Mount Sinai, USA) presented a small study suggesting that moderate sleep apnoea may be cardioprotective in acute myocardial infarction through enhanced collaterals [1].

Dr Shah and colleagues hypothesised that ischaemic preconditioning of the myocardium may have a protective effect in some sleep apnoea (SA) patients during myocardial infarction (MI). The researchers conducted a study to assess whether sleep apnoea is associated with reduced infarct size and enhanced coronary collaterals during an MI by quantifying infarct size (% of left ventricle [LV] infarcted divided by the volume of LV mass). They assessed the score of coronary collaterals using the Rentrop Score (range 0-3, higher scores indicating augmented collaterals).

The study recruited 33 patients (age >21) with ST-elevation MI who underwent percutaneous coronary intervention. Level 3 SA testing was done during hospitalisation. Patients were s...



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