Amongst others, improving the wellbeing of systemic lupus erythematosus (SLE) patients and optimising obesity, hypothyroidism, anaemia, and low vitamin D levels might be useful to improve fatigue, a symptom with a severe impact on quality of life .
Fatigue impacts up to 90% of patients with SLE . The cause of fatigue is most likely multifactorial. Disease activity indices and laboratory markers inconsistently correlate with fatigue severity in SLE populations. An incomplete understanding of fatigue mechanisms limits effective treatment.
Therefore, the aim of the study by Christina Düsing (Universitätsklinikum Düsseldorf, Germany) was to identify additional potentially reversible associations with fatigue to generate a target for future interventions. Data came from 234 consecutively recruited SLE (according to the 1997 ACR criteria) outpatients from the university hospital-based lupus reference centre. Clinical and demographic data from routin...
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