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HoLEP versus PVP in prospective randomised trial

Both holmium laser enucleation of the prostate (HoLEP) and photoselective laser vaporisation of the prostate (PVP) are comparably safe and effective as treatments for benign prostatic hyperplasia (BPH). However, data from a prospective randomised trial suggests that the long-term outcomes of HoLEP surgery may be better.

Dr Yan-Bo Chen (Shanghai Jiao Tong University, China) presented a study that directly compared 2 different laser systems which each produce different qualitative and quantitative effects in tissue [1]. The primary outcome was perioperative safety and 24-month follow-up efficacy data.

A total of 314 BPH patients (estimated prostate volume <60 mL, urodynamics-confirmed BPH) were randomly assigned 1:1 to receive either HoLEP or PVP. Operating times were longer for the patients receiving HoLEP (median 52.3±12.2 minutes) compared with PVP (46.6±12.0 min...



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