Bladder cancer poses a special challenge to urologists due to unclear data concerning the best approach to radical cystectomy with pelvic lymph node dissection. In a debate with Prof. Jens Bedke (University Tübingen, Germany), Prof. Seth Lerner (Baylor College of Medicine, Houston, USA) argued the case for radical cystectomy over robot-assisted radical cystectomy using data from the recent RAZOR trial. In this trial, 350 patients with bladder cancer were randomly assigned to either open or robot-assisted cystectomy, and the primary endpoint was 2-year progression-free survival .
Open radical cystectomy (RC) is historically the treatment of choice for patients who present with invasive disease, progressive disease, or disease refractory to intravesical therapy. Although retrospective data has suggested that robot-assisted radical cystectomy (RARC) is safer than RC, prospective data have been l...
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