Home > Urology > EAU 2019 > Prostate Cancer > The Role of Pelvic Lymph Node Dissection in Prostate Cancer: Extended Vs Standard

The Role of Pelvic Lymph Node Dissection in Prostate Cancer: Extended Vs Standard

Presented By
Dr Karim Touijer, Dr Akshay Sood
Conference
EAU 2019

One prospective study presented showed no benefit of extended PLND, whereas a large retrospective study did point to decreased mortality after PLND.

Dr Karim Touijer et al. (Sloan Kettering Cancer Center, USA) presented a single-centre prospective RCT including 1,480 men with intermediate- to high-risk disease to assess outcomes of limited vs extended lymph node dissection in patients undergoing open, laparoscopic, and robotic prostatectomy for localised prostate cancer. No differences were observed in biochemical-free survival comparing the limited and extended dissection groups.

The patients were randomised to limited pelvic lymph node dissection (PLND; obturator fossa, n=723) or extended PLND (obturator, hypogastric, and external iliac dissection, n=757) groups, which had similar demographics including age, preoperative PSA, Gleason Grade, the presence of extracapsular extension, nodal disease, and seminal vesical invasion. The primary endpoint w...



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