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Over-active bladder

Presented By
Dr Kurt McCammon, Dr Philip Toosz-Hobson, Prof. Martin Michel
EAU 2019
An improved 10-site injection protocol of onabotulinumtoxinA reduces clean intermittent catheterisation use; BMI and UDI are independent predictors of sling surgery outcomes; urgency and nocturia are not being adequately addressed by muscarinic antagonists and possibly the greater family of ß-3 agonists. Dr Kurt McCammon (Eastern Virginia Medical School, USA) compared data from 10-sites of injection of onabotulinumtoxinA vs the standard 20-site approach (both arms administered the same total amount of botox) in females with over-active bladder (OAB). He concluded that 10 injection sites (avoiding the bladder dome) preserved retention, improved quality of life, and was associated with lower clean intermittent catheterisation use. This study tested the outcomes of patients treated with the same number of onabotulinumtoxinA units, but in only 10 injection sites,...

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