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Calcium pyrophosphate deposition disease: an independent risk factor for cardiovascular complications

Presented By
Dr Maaman Bashir, Medical College of Wisconsin, USA
Conference
ACR 2019
A retrospective study showed that patients with calcium pyrophosphate deposition disease (CPPD) have a significantly elevated risk for all-cause mortality and major adverse cardiovascular events, independent from other cardiovascular risk factors [1]. Previous studies have already shown that patients with CPPD not only have precipitation of calcium pyrophosphate crystals in joints but also in the vasculature. While vascular calcification is implicated in the development of cardiovascular disease, studies of cardiovascular risks in CPPD are lacking. With their retrospective cohort study, Dr Maaman Bashir (Medical College of Wisconsin, USA) et al. aimed to assess the risk of cardiovascular events and all-cause mortality in patients with CPPD, compared with those without the disease. In detail, they investigated the risk of major adverse cardiovascular event (MACE) in US veterans with CPPD versus veterans without CPPD using data from the national Veterans Aff...


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