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Atrial myopathy may contribute to dementia risk


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Journal
JAMA
Reuters Health - 22/03/2022 - Impaired left atrial (LA) function may be a risk factor for dementia, according to an exploratory analysis of data from the Atherosclerosis Risk in Communities (ARIC) study. The analysis found statistically significant associations between measures of lower LA function and an increased risk of subsequent dementia, report Dr. Wendy Wang of the University of Minnesota, in Minneapolis, and colleagues. This analysis introduces "intriguing concepts" regarding how atrial myopathy, however defined, may contribute to dementia risk, say the authors of an editorial published with the study in JAMA. The findings are based on 4,096 older ARIC participants (mean age, 75 years; 60% women; 225 Black) without prevalent atrial fibrillation (AF) or stroke who underwent two-dimensional echocardiography between 2011 and 2013 and were followed until the end of 2019. Atrial myopathy was defined using a number of different measures of LA size (m...


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