Home > Cardiology > ACC/WCC 2020 > Atrial Fibrillation/Acute Coronary Syndrome > Fewer adverse events with ticagrelor monotherapy after 3 months DAPT

Fewer adverse events with ticagrelor monotherapy after 3 months DAPT

Presented By
Prof. Y.S. Jang, Yonsei University, South Korea

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Conference
ACC 2020
Trial
TICO
Ticagrelor monotherapy after 3-month dual antiplatelet therapy (DAPT) has shown a significantly lower risk of net adverse clinical events (NACE) than the currently recommended 12-month DAPT with ticagrelor and aspirin, with the reduced risk mainly due to decreased major bleeding [1].  The objective of the TICO trial, presented by Prof. Yang Soo Jang (Yonsei University, South Korea), was to investigate ticagrelor monotherapy after 3 months of DAPT versus ticagrelor-based, 12-month DAPT for patients with acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI) with new-generation, drug-eluting stents. The study enrolled 3,065 ACS patients (mean age 61 years) undergoing PCI with second-generation, ultrathin, biodegradable, polymer-coated, sirolimus-eluting stents. All patients received ticagrelor plus aspirin for 3 months after ...


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