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Weight loss associated with increased mortality risk in heart failure patients

Presented By
Dr Nuno Melo, Centro Hospitalar e Universitário de São João, Portugal
Conference
HFA 2021
A retrospective study examined the impact of changes in weight on all-cause mortality of patients with heart failure (HF). More than 5% body weight loss over 1 year was associated with an increased likelihood of mortality in initially normal or overweight but not in obese patients. Although obesity increases the development of HF, being overweight or obese compared with normal weight is associated with survival advantages in chronic HF patients [1]. This phenomenon is known as the obesity paradox. With this in mind, Dr Nuno Melo (Centro Hospitalar e Universitário de São João, Portugal) and his colleagues were interested in the impact of weight changes in HF patients [2]. They conducted a retrospective cohort study including 589 adult patients who were all treated in an HF clinic between January 2012 and May 2018. The study assessed their mortality risk in association with body weight trajectories. The study participants had a reduced ejection fracti...


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