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Residual pulmonary obstruction may predict risk of VTE recurrence

Presented By
Dr Robin Chaux, University Hospital St. Etienne, France
ISTH 2020
A pooled analysis identified initial pulmonary vascular obstruction index (PVOI) >35% and residual PVOI >5% as cut-off values for prognosis of venous thromboembolism (VTE) recurrence after a first pulmonary embolism (PE). Experiencing a first episode of PE entails a substantial risk of VTE recurrence and case fatality [1]. “Guidelines do not really take into account all the variability between patients, e.g. for a patient with an unprovoked PE, a life-long anticoagulant therapy is recommended, but only one third of these patients will have benefits from this treatment, leaving the others exposed to hard to justify haemorrhagic risks,” Dr Robin Chaux (University Hospital St. Etienne, France) explained, pointing to a need of improved scores to predict recurrence [2]. A promising candidate for risk stratification is the PVOI level. “In literature, significant associations were found between PVOI and VTE recurrence, but the result...

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