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SAVR an option for many low-risk patients excluded from clinical trials


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Journal
Journal of the American College of Cardiology
Reuters Health - 19/01/2021 - Many patients who are excluded from clinical trials comparing transcatheter aortic-valve replacement (TAVR) with surgical aortic-valve replacement (SAVR) appear to do well with the latter approach, according to researchers in Canada. "In real-world clinical practice, about one-half of low-risk patients with severe aortic stenosis undergoing SAVR have at least one characteristic prompting exclusion from randomized comparisons to TAVR," Dr. Josep Rodes-Cabau of Laval University, in Quebec City, told Reuters Health by email. "In these cases, SAVR was associated with similar outcomes to the rest of the low-risk SAVR recipients, and the observed mortality was even lower than that estimated by surgical risk scores, with the exception of those patients with concomitant mitral/tricuspid valve disease, who exhibited an increased risk," he said. Dr. Rodes-Cabau and colleagues examined data on more than 6,700 patients with severe aortic ste...


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