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TAVR may be best choice for valve replacement after mediastinal radiation


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Journal
JACC: Cardiovascular Interventions
Reuters Health - 24/11/2020 - In patients who have previously undergone mediastinal radiation and require aortic-valve replacement, transcatheter aortic-valve replacement (TAVR) appears to offer advantages over surgical aortic-valve replacement (SAVR), according to a large database study. Compared with SAVR, "TAVR procedures are increasingly performed among patients with prior mediastinal radiation, and . . . they are associated with lower hospital mortality and bleeding and respiratory complications, as well as shorter hospitalization," Dr. Hani Jneid of the Baylor School of Medicine and the Michael E. DeBakey VA Medical Center, in Houston, Texas, told Reuters Health by email. In a paper in JACC: Cardiovascular Interventions, Dr. Jneid and colleagues note that although mediastinal radiation is an important treatment for malignancies it can lead to radiation-associated cardiopulmonary disease, with aortic stenosis being the most common valvular consequence. P...


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