Home > Dermatology > Merkel cell cancers recur more often than other skin cancers, usually within three years

Merkel cell cancers recur more often than other skin cancers, usually within three years


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Journal
JAMA Dermatology
Reuters Health - 03/03/2022 - Merkel cell carcinoma (MCC) recurs much more often than other skin cancers, and most recurrences are within three years of a diagnosis, researchers say. MCC stage seems to be prognostic, and can be used to inform surveillance intensity. "We spent years being frustrated by our inability to accurately tell patients what the risk is that their MCC will come back," Dr. Paul Nghiem of the University of Washington in Seattle told Reuters Health by email. "Because recurrences do not always lead to death, and sometimes a recurrence precedes death by many years, it was hard to know what to tell patients besides general concepts like 'risk goes up with cancer stage', and 'risk falls after years of no recurrence.'" "It was reassuring to see that our larger cohort had a 40% recurrence risk, in the middle of prior reports of 27%-77%," he said. "Surprisingly, when we split our population into three groups based on the year patients were diagno...


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