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Olson grade, need for more treatment are markers of increased skin cancer risk in actinic keratoses

Journal
JAMA Dermatology
Reuters Health - 06/05/2022 - In patients with multiple actinic keratoses (AKs), Olson grade III and the need for more treatment were identified as markers for increased risk of cutaneous squamous cell carcinoma (cSCC) in a secondary analysis of a randomized trial. "There is an alarming increase in sun damage resulting in AK and cSCC," Dr. Shima Ahmady of Maastricht University Medical Center in the Netherlands told Reuters Health by email. "In a population-based cohort study in the Netherlands, AK affected 49% of men and 28% of women aged 50 years and older." (https://bit.ly/3kIsNZB) "We found that the risk of invasive cSCC was significantly higher in patients with Olsen grade III AK (AK with severe keratosis) compared to AK with mild keratosis," she noted. "In patients with Olsen grade III AK who needed additional treatment, more than a third developed an invasive cSCC within four years. Close foll...


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