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Comparable safety profiles of biological therapies in elderly patients with IBD

Presented By
Dr Gustavo DrĂĽgg Hahn, McGill University Health Center, Canada
Conference
ECCO 2022
A systematic review comparing the safety profiles of biological therapies in elderly patients with inflammatory bowel disease (IBD) did not reveal significant differences in the rate of adverse events (AEs) between the different treatments. However, infusion/injection reactions occurred more often in patients treated with anti-TNFs. The authors concluded that larger studies are needed to establish sequencing recommendations of biological therapies in this population. Dr Gustavo DrĂĽgg Hahn (McGill University Health Center, Canada) and colleagues conducted a systematic review and meta-analysis to study the safety profiles of biological therapies in elderly patients with IBD [1]. In total, 17 studies assessing the safety profiles of anti-TNFs, vedolizumab, and ustekinumab in participants with IBD aged 60 years or older were included in the systematic review. No significant difference was detected in the rate of AEs for participants treated with anti-TN...


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