Home > Gastroenterology > Machine perfusion boosts outcomes of liver transplant

Machine perfusion boosts outcomes of liver transplant


Notice: Undefined index: new_doi_fields in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/template-parts/content-structured.php on line 22

Notice: Trying to access array offset on value of type null in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/template-parts/content-structured.php on line 22

Notice: Trying to access array offset on value of type null in /home/daan/projects/medicalconferences_dev/wp-content/themes/writers-blogily-child/template-parts/content-structured.php on line 22
Journal
JAMA Surgery
Reuters Health - 05/01/2022 - When preparing deceased-donor livers for transplant, portable normothermic blood-based machine perfusion improves transplant outcomes and leads to more livers being transplanted than ischemic cold storage, the current standard, according to results of the PROTECT trial. Machine perfusion (MP) is "poised to change the face of liver transplant," write the authors of an editorial published with the study in JAMA Surgery. The PROTECT trial compared outcomes for 300 individuals who were actively listed for liver transplant on the United Network of Organ Sharing national waiting list and were randomly assigned to receive livers preserved using either MP or ischemic cold storage. Livers that underwent normothermic MP had significantly less early allograft dysfunction, decreased histologic evidence of ischemia-reperfusion injury, and decreased ischemic biliary complications at six and 12 months relative to livers preserved in cold storag...


Please login to read the full text of the article.


If you have no account yet, please register now.





Posted on