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New normal metrics should be used to assess gastroesophageal reflux, researchers say


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Reuters Health - 26/11/2020 - New normal values for esophageal impedance-pH metrics, adjusted for region and testing system, should be used to assess gastroesophageal reflux, researchers say, although some experts remain unconvinced. "We have finally the best set of normal values using impedance-pH metry after more than 15 years, and we are using this technique for clinical diagnosis," Dr. Daniel Sifrim of Barts and The London School of Medicine and Dentistry told Reuters Health by email. Ambulatory impedance-pH monitoring is an established approach for investigating esophageal symptoms suspicious for gastroesophageal reflux disease (GERD), but it remains unclear whether measurements obtained using different systems or across world regions are comparable. Moreover, normal values have been based on small groups of healthy volunteers from only one or two countries. Dr. Sifrim and colleagues analyzed 541 impedance-pH tracings from healthy asymptomatic subjects f...


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