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CAR-T outcomes similar among Black, Hispanic, white, Asian patients

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Blood Marrow Transplantation
Reuters Health - 10/05/2022 - Black and Hispanic cancer patients who underwent CAR-T therapy at a single center had comparable outcomes to their white and Asian counterparts, researchers say. "We were not surprised at the outcome, but our findings helped us resolve the unknown, and we feel that much more confident about the treatments we're providing our community," Dr. Mendel Goldfinger of Montefiore Health System and Albert Einstein College of Medicine in New York City told Reuters Health by email. "There are differences in disease biology and immune responses for different ethnic groups, so we wanted a data-driven approach to ensuring that we are providing the best care possible." "Our findings that minorities have equal outcomes and side effects from CAR-T cell therapy should give physicians confidence about use of these therapies, particularly for individuals underrepresented in clinical trials," he said. The real-world exploratory retrospective cohort s...


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