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Renal denervation yields meaningful and lasting BP reductions


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Journal
The Lancet
Reuters Health - 14/04/2022 - Radiofrequency renal denervation led to clinically meaningful blood-pressure lowering out to three years, independent of concomitant antihypertensive medications and without major safety events, in patients with treatment-resistant hypertension enrolled in the SPYRAL HTN-MED trial. The three-year study findings were presented at the American College of Cardiology 2022 Scientific Session and simultaneously published in The Lancet. The study used the Symplicity Spyral renal denervation system from Medtronic, which funded the study. The randomized study enrolled 80 adults with uncontrolled hypertension not responding to up to three antihypertensive medications; 38 underwent renal denervation and 42 underwent a sham procedure. "Mean ambulatory systolic and diastolic blood pressure were significantly reduced from baseline in the renal denervation group, and were significantly lower than the sham control group at 24 and 36 months, desp...


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