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Shorter course of anticoagulant therapy adequate for provoked VTE in children


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Journal
JAMA
Reuters Health - 11/01/2022 - For children with acute provoked venous thromboembolism (VTE), six weeks of anticoagulant therapy is as effective as a three-month course of anticoagulant therapy, results of a new clinical trial suggest. "When treatment should be stopped is as important as when it should be started," say the authors of an editorial published with the study in JAMA. "The findings suggest that anticoagulant therapy could be stopped sooner than currently recommended and that doing so is likely to be as safe as longer treatment. Quality of life may be improved in many children by decreasing the duration of subcutaneous injections," write Dr. Jacques Lacroix of the University of Montreal, in Canada, and colleagues. Among patients younger than 21 years, the optimal duration of anticoagulant therapy for VTE is unknown. However, the standard of care for provoked VTE (that is, VTE temporally associated with a prothrombotic clinical risk factor) has been ...


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