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Disrupted conscious access linked to altered brain connectivity in psychosis


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Journal
The Journal of Neuroscience
Reuters Health - 25/11/2020 - People with schizophrenia have a higher threshold for conscious perception, which correlates with altered cerebral connectivity, new findings show. Individuals who had bipolar disorder with psychotic features also had deficits in conscious access compared with those with bipolar disorder but no psychosis and with healthy controls, Dr. Josselin Houenou of APHP, Hopitaux Universitaires Mondor in Creteil, France, and colleagues report in The Journal of Neuroscience. The findings support the global neuronal workspace (GNW) theory, which posits that conscious access requires global activation of long-distance neuronal networks. "The GNW theory assumes that conscious perception arises from the stabilization of neuronal activity within a distributed network, rendering a specific piece of information reportable to others," Dr. Houenou and his colleagues explain. Increased threshold for conscious perception and altered cerebral con...


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