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No new safety signals in ofatumumab open-label data


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Conference
MS Virtual 2020
Trial
ALITHIOS, ASCLEPIOS I, ASCLEPIOS II, APLIOS
Only a few weeks prior to the MSVirtual 2020, the fully human anti-CD20 monoclonal antibody ofatumumab was approved by the FDA for the treatment of relapsing forms of MS. In the open-label extension study ALITHIOS, ofatumumab's very good safety profile was consistent with data from the core phase 3 ASCLEPIOS I/ASCLEPIOS II trials [1,2]. The indication of ofatumumab is to include clinically isolated syndrome (CIS), relapsing-remitting MS, and active secondary progressive MS in adults. In the ASCLEPIOS trials, ofatumumab demonstrated superior efficacy ...


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