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Risk of neurotoxic effects of prenatal antipsychotic exposure appears low, but questions linger


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Journal
JAMA Internal Medicine
Reuters Health - 28/03/2022 - Babies exposed to antipsychotic medication in the womb do not appear to have a "meaningfully increased" risk of neurodevelopmental disorders, according to a large study.  "Although antipsychotic drugs cross the placenta and animal data suggest potential neurotoxic effects, information regarding human neurodevelopmental teratogenicity is limited," researchers note in JAMA Internal Medicine.  The findings suggest that antipsychotic medications "may not have important neurotoxic effects," although a "potential signal" identified for aripiprazole requires further study, say Dr. Loreen Straub of Brigham and Women's Hospital in Boston an...


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