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MRI-based nomograms may predict lymph node metastasis, survival in early breast cancer


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Journal
JAMA Network Open
Reuters Health - 16/12/2020 - Multiparametric magnetic resonance imaging (MRI)-based radiomic nomograms predicted axillary lymph node metastasis (ALNM) and disease-free survival (DFS) in early breast cancer in a retrospective study in China. "The machine learning MRI radiomic signature tool could effectively classify early-stage breast cancer patients into groups with different risks of ALNM and DFS, and (may) eventually result in a noninvasive approach to guide future clinical practice," Drs. Herui Yao and Erwei Song of Sun Yat Sen University in Guangzhou told Reuters Health by email. As reported in JAMA Network Open, the study included 1,214 women (median age, 47) diagnosed with early-stage breast cancer at four hospitals in China between 2007-2019, and randomly divided into development (69.9%) and validation (30.1%) cohorts. All participants underwent preoperative MRI scans and were treated with surgery and sentinel lymph node biopsy or ALN dissection. The...


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