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Rising thyroid cancer incidence in youth may suggest overdiagnosis


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Journal
The Lancet Diabetes & Endocrinology
Reuters Health - 29/01/2021 - Global incidence of thyroid cancer among children and adolescents has climbed rapidly in recent years despite low mortality, with wide variation among countries, according to a new study whose authors suggest that overscreening and overdiagnosis are playing a role. Researchers examined data on thyroid cancer incidence in 49 countries and territories and on mortality in 27 countries for youth aged 0-19 years old, using records from the World Health Organization as well as two other cancer incidence registries. The analysis included 8,049 thyroid cancer cases from 2008 to 2012. Overall, age-standardized incidence from 2008 to 2012 ranged from as low as 0.4 per 1 million person-years in Uganda and Kenya to as high as 13.4 per 1 million person-years in Belarus, the study found. During this period, incidence rates ranged from 0.6 to 20.4 cases per 1 million per-years for girls and from 0.3 to 6.8 cases per 1 million person-years for boys.


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