Home > Pulmonology > ATS 2022 > SPRINTER still in the running?

SPRINTER still in the running?

Presented By
Dr Phillip Monk, Synairgen Research LtD, UK
Conference
ATS 2022
Trial
Phase 3, SPRINTER
A post hoc analysis of the SPRINTER trial suggests that the inhaled, interferon-β investigational agent for COVID-19, known as SNG001, may provide a beneficial effect with respect to prevention of severe disease or death, despite not meeting its primary endpoint. These results provide a potential clinical rationale to continue the investigation of SNG001 in progression and/or mortality in hospitalised patients with COVID-19. Dr Phillip Monk (Synairgen Research LtD, UK) presented the post hoc analyses of the phase 3, randomised, placebo-controlled, double-blind, SPRINTER study (NCT04732949) [1]. The rationale behind this trial was based on recent promising phase 2 results [2]. SPRINTER assessed the efficacy and safety of SNG001 for the treatment of adults hospitalised due to COVID-19 who required treatment with supplemental oxygen by mask or nasal prongs. Pat...


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