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Expected clinical trajectory of severe bronchiolitis doesn’t pass muster in new study


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Journal
Pediatrics
Reuters Health - 22/10/2020 - A new study challenges the notion that bronchiolitis symptoms peak on days three to five of illness in hospitalized infants. "Severe bronchiolitis is a heterogeneous condition with an unpredictable clinical course. Practitioners should exercise caution when making clinical decisions or providing anticipatory guidance on the basis of symptom duration," Dr. Alan Schroeder of Stanford University in California and colleagues say in a paper in Pediatrics. Bronchiolitis makes up roughly 18% of all hospitalizations in infants and young children. It's been described as having an "expected clinical trajectory" with symptom severity peaking between three and five days. But Dr. Schroeder and colleagues found no association between day of illness at admission and clinically important outcomes in bronchiolitis hospitalizations. Their findings are based on data from two multicenter prospective studies involving 746 children under 2 years of ag...


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