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Lung-cancer screening in at-risk never-smokers catches early disease


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Journal
IASLC World Conference on Lung Cancer
Reuters Health - 03/02/2021 - A study from Taiwan supports the value of low-dose computed tomography (LDCT) lung cancer screening in people who have never smoked but have risk factors for lung cancer. The Taiwan Lung Cancer Screening for Never Smoker Trial (TALENT) detected lung cancer in 2.6% of never-smokers, which is more than the 1.1% and 0.9% lung-cancer detection rates from the U.S. National Lung Screening Trial (NLCST) and the NELSON trial, respectively, which screened heavy smokers. Dr. Pan-Chyr Yang of the National Taiwan University College of Medicine, in Taipei, reported the findings at the International Association for the Study of Lung Cancer (IASLC) virtual World Conference on Lung Cancer. In Taiwan, lung cancer is the leading cause of cancer mortality, and 53% of these deaths occur in people who have never smoked. Lung cancer among never-smokers in East Asia represents a distinct disease: The genomic profile, carcinogenesis and pattern of progr...


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