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More pros than cons for the use of statins in RA

Presented By
Dr Gulsen Ozen, University of Nebraska Medical Center, NE, USA
ACR 2021
Rheumatoid arthritis (RA) patients benefit from significant reductions in cardiovascular and all-cause mortality when treated with statins. The advantages of statin treatment outweigh the modest risk of diabetes resulting from the therapy. “Only few studies so far have shown that statins improve endothelial function, atherosclerotic plaques, and even disease activity in patients with RA. Few studies also showed that statins can reduce cardiovascular disease and all-cause mortality in RA with a wide range of magnitude,” Dr Gulsen Ozen (University of Nebraska Medical Center, NE, USA) pointed out [1]. Unlike for the general population, data on the type 2 diabetes mellitus (T2DM) risk associated with statin use is still limited in RA patients. “As we know, T2DM is an important concern in RA, because it not only increases and worsens cardiovascular outcomes but also some infection and cancer incidences and outcomes which are other causes of mor...

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