Home > Rheumatology > EULAR 2022 > Steep increase of mortality in RA patients with comorbid depression

Steep increase of mortality in RA patients with comorbid depression

Presented By
Dr Jens Kristian Pedersen, Odense University Hospital, Denmark
Conference
EULAR 2022
A large register study in Denmark detected a substantially higher mortality risk for patients with rheumatoid arthritis (RA) who had comorbid depression. Especially younger patients are at risk: an over 6-fold risk amplification was found for those under 55 years. “In patients with RA, the occurrence of depression is high,” Dr Jens Kristian Pedersen (Odense University Hospital, Denmark) stated [1]. He presented a cohort study that investigated the mortality risk in patients with incident RA and depression. Data was collected from various nationwide Danish registries. The presence of depression was defined as the first filling of an antidepressant prescription. The follow-up period for the all-cause mortality risk was from January 2008 to December 2018. Included in the analysis was data on 11,071 RA patients equalling 56,993 person-years of follow-up. About 10% of the participants (n=1,095) had a filling of antidepressants during the follow-up perio...


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