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Best of EAU: Immune cell populations have prognostic value in RCC

Presented By
Dr Alberto Breda, Autonomous University of Barcelona, Spain
Conference
EAU 2021
During the Best of EAU21 abstracts session, Dr Alberto Breda (Autonomous University of Barcelona, Spain) highlighted 6 representative abstracts on renal cancer, including 4 from Italy, his country of origin [1]. Assessment of immune cell populations on nephrectomy specimens was shown to have prognostic value in renal cell carcinoma (RCC). Another study externally validated the guidelines for Von-Hippel Lindau disease (VHL) genetic testing. Furthermore, a study on the oncological outcomes of neoadjuvant target therapy and 3 studies on robot-assisted partial nephrectomy were presented. As opposed to other tumour types, higher levels of tumour-infiltrating lymphocytes have been associated with worse outcomes on systemic treatment in metastatic RCC. Investigators from Leuven, Belgium, included 143 patients of whom 103 (72.0%) experienced disease recurrence and 67 (46.9%) died of RCC [2]. The aim was to explore the impact of immune and stromal cell populations ...


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